CISA has added one new vulnerability to its Known Exploited Vulnerabilities (KEV) Catalog , based on evidence of active exploitation. CVE-2025-53521 F5 BIG-IP Remote Code Execution Vulnerability This type of vulnerability is a frequent attack vector for malicious cyber actors and poses significant risks to the federal enterprise. Binding Operational Directive (BOD) 22-01: Reducing the Significant Risk of Known Exploited Vulnerabilities established the KEV Catalog as a living list of known Common Vulnerabilities and Exposures (CVEs) that carry significant risk to the federal enterprise. BOD 22-01 requires Federal Civilian Executive Branch (FCEB) agencies to remediate identified vulnerabilities by the due date to protect FCEB networks against active threats. See the BOD 22-01 Fact Sheet for more information. Although BOD 22-01 only applies to FCEB agencies, CISA strongly urges all organizations to reduce their exposure to cyberattacks by prioritizing timely remediation of KEV Catalog vulnerabilities as part of their vulnerability management practice. CISA will continue to add vulnerabilities to the catalog that meet the specified criteria .